Qihengxing enzyme engineering platform focuses on genetic engineering enzyme modification and reaction system optimization. Through directed evolution and AI high-throughput screening, it has developed high-performance enzymes such as anti-inhibition polymerases and high-sensitivity enzymes. Combined with a unique buffer system, it significantly improves PCR/qPCR performance, meets the needs of diverse molecular biology experiments, and promotes breakthroughs in scientific research and diagnosis

Case Details

Genetically engineered enzymes have become the darling of capital.
According to Qihengxing's understanding of enzyme engineering, gene mutation or gene recombination has a "certain" effect on improving the "specific" performance of enzymes, but only "Enzyme + Buffer System" Perfect cooperation can bring out excellent performance. At present, the performance of similar products on the market varies greatly, and a large proportion is caused by the buffer. Qihengxing practices the spirit of seeking truth from facts. In the development of PCR/qPCR systems, it fully respects the natural biological activity of enzymes, deeply studies and understands the mechanism of action of enzymes and the dynamic process of system reactions. Through the study of reaction systems, according to different application scenarios, it develops products suitable for different application needs. Maximize the protection and utilization of enzymes and improve the performance of reaction systems. The company has gradually accumulated and refined the working guidelines for the development of "reaction systems".

Qihengxing has developed a method for evaluating enzyme performance and function and has applied for a national invention patent; the related enzymes that have been developed have been applied to the company's product series.

Enzyme performance and function evaluation: Qihengxing Biotechnology has developed a set of enzyme performance and function evaluation methods and applied for a national invention patent for it, which shows that the company has independent intellectual property rights and innovation capabilities in the field of enzyme engineering.

R&D concept: Qihengxing Bio focuses on the bottom-level architecture in R&D, similar to laying the foundation for a building, and is committed to the creative process from zero to one, which enables the company to achieve innovation and breakthroughs in the field of enzyme engineering.

Interdisciplinary requirements: Qihengxing Bio has high requirements for its R&D personnel, requiring them to not only understand biology, but also mathematics, physics and chemistry. These basic skills are very important for R&D.

Qihengxing Bio uses directed evolution to carry out gene mutation modification and recombination, constructs inhibitory polymerases and enzyme evaluation methods with independent intellectual property rights, repeatedly screens out excellent enzymes under AI high-throughput, and forms its own rich polymerase library, such as inhibitor-resistant series and high-sensitivity series.